Playa de las Américas is the best pick for nightlife, no contest really. This is where you go if you want late bars, clubs, music spilling out onto the street, and people still out when most other places have gone quiet.
It’s not subtle, and that’s the point. Costa Adeje has a few nicer bars, but it’s much more of a sit down and chat kind of place. Los Cristianos has some life too, though nothing like Américas.
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If nightlife is the main reason for your trip, then Playa de las Américas is the obvious answer.